If you’re living with depression that just won’t let up, even after trying multiple medications or therapies, you’re not alone—and you’re not out of options. Totally Psyched! In Winter Garden, FL, we specialize in helping people who’ve hit a wall with traditional approaches. One of the most exciting developments in mental health care right now is Spravato, and yes—it’s changing lives.
Spravato is an FDA-approved ketamine nasal spray designed to treat treatment-resistant depression, and it’s making waves for all the right reasons. Unlike standard antidepressants that may take weeks to start working (if they work at all), Spravato acts on a different system in the brain, and patients often notice changes within days. That’s a huge shift in what depression treatment can look like, and we’re proud to offer it right here at Totally Psyched!
What Is Spravato, Really?
Let’s keep this clear and simple: Spravato is a medication made from esketamine, which is a derivative of ketamine, a substance originally used as an anesthetic. Over the past decade, researchers have discovered that ketamine and esketamine also have powerful antidepressant effects, particularly for people who haven’t responded to other forms of treatment.
Unlike traditional antidepressants, which work by influencing serotonin or dopamine levels, Spravato targets glutamate, the most abundant neurotransmitter in your brain. Why is this important? Because this different mechanism may help explain why esketamine therapy can be effective even when other treatments fall short.
Spravato is administered as a nasal spray for severe depression in a clinical setting, so it’s fast-acting and controlled. It’s not something you pick up at a pharmacy or take on your own at home. At Totally Psyched!, we guide and support you throughout the process, making sure you’re safe, comfortable, and heard.
Who Can Spravato Help?
If you’ve already tried at least three different antidepressants and your depression symptoms are still lingering—or even worsening—you may be a candidate for Spravato treatment. It’s designed for people with treatment-resistant depression, a frustrating and deeply personal experience that can leave you feeling like you’ve run out of options. But this is where things can change.
Spravato isn’t just about symptom relief—it’s about hope. For many patients, this depression medication can bring clarity, emotional balance, and a renewed ability to function in daily life. That includes getting back to work, connecting with loved ones, or simply enjoying the little things again.
What’s also important to know: Spravato is often used alongside an oral antidepressant, not as a replacement. The combination can be incredibly powerful, especially when guided by a provider who understands the nuances of mental health treatments—like our team here at Totally Psyched!
What Happens During a Spravato Appointment?
We get it: trying something new, especially a medical treatment, can feel intimidating. But at Totally Psyched!, we make the process of starting Spravato as smooth, transparent, and supportive as possible.
When you arrive for your appointment, we’ll bring you to a quiet, private room where you’ll be able to relax. A trained medical provider will explain the process, answer any questions you have, and walk you through the steps. The ketamine nasal spray will be self-administered under our supervision. Once that’s done, you’ll remain in the room with us for a short time so we can monitor your response and ensure your safety. During this time, many people simply relax—some listen to calming music, journal, or just sit quietly. It’s a reflective, peaceful environment. We also have the option to combine your Spravato treatment with a psychotherapy session from one of our highly qualified psychotherapists. More information is available upon request.
Our goal is to create a supportive space where you feel empowered and cared for. Spravato treatment may be medical, but at Totally Psyched!, it’s also deeply personal.
Let’s Talk About the Science (Without the Jargon)
So what is it about ketamine that makes it so different—and why is it making such an impact in the field of mental health?
Here’s the short version: ketamine for depression has been shown to rapidly reduce symptoms, especially in people who haven’t responded to traditional treatments. Unlike most antidepressants, which may take 4–6 weeks to kick in, ketamine and esketamine therapy can work within hours or days. That’s a massive relief when every day feels like a mountain to climb.
Spravato’s active ingredient, esketamine, is a refined version of ketamine, meaning it’s more potent and designed specifically for mental health use. It helps create new connections between brain cells and restores function to areas of the brain that may have been impacted by chronic stress or trauma. In many ways, it helps your brain reboot.
Ketamine treatment isn’t just about chemistry—it’s about giving people a new way forward, especially when other options haven’t worked.
You Are Not Alone—and You Deserve to Feel Better
Depression isn’t just “feeling down.” It’s a complex, often invisible illness that can make even the smallest tasks feel impossible. And if you’ve been living with it for a long time—especially without relief—it’s easy to wonder if anything can actually help.
But here’s the truth: help is out there. And more importantly, you are not alone.
At Totally Psyched!, we’ve created a welcoming, stigma-free space where mental health treatment feels less like a clinical checklist and more like a conversation. We believe in meeting people where they are and offering cutting-edge options like ketamine therapy for depression when it’s appropriate.
We know how isolating treatment-resistant depression can be. But Spravato may be the tool that finally makes a difference—and we’re here to walk you through the process with compassion, experience, and zero judgment.
Spravato for Depression at Totally Psyched! Near Orlando, FL
If you’ve been searching for a new path forward—one that actually addresses your depression instead of just masking it—Spravato treatment at Totally Psyched! could be right for you. We know how exhausting it can be to feel like you’ve tried everything, and we want to offer you comprehensive care, cutting-edge science, and a fresh perspective on what mental health treatment can look like.
Our team is here to answer your questions, talk through your concerns, and help you decide if Spravato is right for you. You don’t have to keep waiting and hoping things will improve on their own. Take the first step toward feeling better—request an appointment with us today. Let’s figure it out together, because healing shouldn’t be a mystery—and you deserve to feel like yourself again.
